Recombinant QKI anticorps

N° du produit ABIN7828501

Cet anticorps Lapin Monoclonal détecte spécifiquement QKI dans WB et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant QKI anticorps (ABIN7828501)

Antigène: QKI (Protein Quaking (QKI))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp QKI est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: A575

Détail du produit anti-QKI anticorps

Fonction: Recombinant QKI Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human QKI fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:3000,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur QKI

Antigène: QKI (Protein Quaking (QKI))

Autre désignation: QKI

Sujet: QKI,Hqk,QK,QK1,QK3,hqkI,HKQ,QKI is a member of the signal transduction and activator of RNA (STAR) protein family of RNA-binding proteins. Mutations in the mouse Qki locus results in impaired myelin formation resulting in tremors. QKI proteins exist as homodimers, and disruption of the dimerization process is lethal in mice. QKI exists in different isoforms that differ in their C-terminus, resulting in unique subcellular localizations. The nuclear isoform of QKI, QKI-5, is involved in regulation of alternative splicing of MAG mRNA, which encodes for a protein important for myelin sheath formation and maintenance. QKI has also been implicated in schizophrenia and oligodendrocyte differentiation. QKI can function as a tumor suppressor, as it is regulated by p53 to stabilize miRNAs that regulate TGF-β signaling. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 38 kDa

Observed MW: 38 kDa

UniProt: Q96PU8