Recombinant RUNX3 anticorps

N° du produit ABIN7828537

Cet anticorps Lapin Monoclonal détecte spécifiquement RUNX3 dans WB et IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant RUNX3 anticorps (ABIN7828537)

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RUNX3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: A518

Détail du produit anti-RUNX3 anticorps

Fonction: Recombinant RUNX3 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human RUNX3 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IP 1:25-1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur RUNX3

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Autre désignation: RUNX3

Sujet: AML,RUNX,CBFA,Oncogene AML,Core-binding factor subunit alpha,Runt-related transcription factor,PEBP2A,RUNX3,AML2,CBFA3,PEBP2aC,Acute myeloid leukemia 2 protein,Core-binding factor subunit alpha-3,Oncogene AML-2,Runt-related transcription factor 3,PEBP2A3,RUNX3 is a member of the Runt family of transcription factors, playing an important role in the suppression of gastric epithelium cell proliferation, dorsal root ganglia neurogenesis, and T cell differentiation. RUNX3 is also involved in Caspase-3-dependent apoptosis. Protein complexes containing RUNX3 and various transcription factors, such as Smads or β-catenin/TCF4, have tumor suppressor activity and regulate downstream target gene transcription. While typically localized to the nucleus, RUNX3 can be tyrosine phosphorylated and located in the cytoplasm of many cancer cells. This mislocalization of RUNX3 abolishes its tumor suppressor function and contributes to tumorigenesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 46 kDa

Observed MW: 44-46 kDa The actual band is not consistent with the expectation.

UniProt: Q13761