Recombinant SATB1 anticorps

N° du produit ABIN7828546

Cet anticorps Lapin Monoclonal détecte spécifiquement SATB1 dans WB, IHC et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant SATB1 anticorps (ABIN7828546)

Antigène: SATB1 (SATB Homeobox 1 (SATB1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SATB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: A355

Détail du produit anti-SATB1 anticorps

Fonction: Recombinant SATB1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human SATB1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:200-1:1000,FCM 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur SATB1

Antigène: SATB1 (SATB Homeobox 1 (SATB1))

Autre désignation: SATB1

Sujet: SATB,SATB1,Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma. Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g., PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 86 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: Q01826

Pathways: Caspase Cascade in Apoptosis, Activated T Cell Proliferation