Recombinant SV2A anticorps

N° du produit ABIN7828606

Cet anticorps Lapin Monoclonal détecte spécifiquement SV2A dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant SV2A anticorps (ABIN7828606)

Antigène: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SV2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A710

Détail du produit anti-SV2A anticorps

Fonction: Recombinant SV2A Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000,IHC 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur SV2A

Antigène: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Autre désignation: SV2A

Sujet: KIAA,PSEC,SV2,SV2A,KIAA0736,PSEC0174,SV2s are a family of synaptic vesicle proteins expressed in both neurons and endocrine cells. SV2s function in the regulation of synaptic vesicle traffic, cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation and the facilitation of synaptic transmission. There are three isoforms of SV2: SV2A, SV2B and SV2C. Each of these isoforms are structured similarly but expressed varyingly. SV2C, a minor isoform of SV2, expressed in a small subset of neurons located within the basal forebrain, midbrain and brainstem. SV2B, a major isoform of SV2 is expressed more abundantly, although rarely without the coexpression of SV2A. SV2A, the other major isoform of SV2 is the most widely expressed. SV2A is located in the presynaptic nerve terminals of almost every neuron throughout the nervous system. In addition, it is also located in most neuroendocrine secretory granules. SV2A has been identified as a critical protein for proper function of the central nervous system and has been linked to the physiopathology of epilepsy. In addition to the epileptic affects of this protein, mutations in it have also been seen to result in schizophrenia. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 83 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: Q7L0J3