Recombinant TYMS anticorps

N° du produit ABIN7828623

Cet anticorps anti-TYMS Monoclonal Lapin (Clone A524) (ABIN7828623) détecte spécifiquement TYMS dans IF, WB et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant TYMS anticorps (ABIN7828623)

Antigène: TYMS (Thymidylate Synthetase (TYMS))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TYMS est non-conjugé

Application: Immunofluorescence (IF), Western Blotting (WB), Flow Cytometry (FACS)

Clone: A524

Détail du produit anti-TYMS anticorps

Fonction: Recombinant Thymidylate Synthase Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Thymidylate Synthase fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur TYMS

Antigène: TYMS (Thymidylate Synthetase (TYMS))

Autre désignation: Thymidylate Synthase

Sujet: HST,OK/SW-cl,TYMS,HST422,TMS,TS,thymidylate synthase,OK/SW-cl.29,HST422,thymidylate synthase,TMS,thymidylate synthetase,Thymidylate synthase is a homodimer composed of two 30 kDa subunits, which catalyze the methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), an essential step in the formation of thymine nucleotides. Thymidylate synthase is an intracellular enzyme that provides the sole de novo source of thymidylate, making it a required enzyme in DNA biosynthesis with activity highest in proliferating cells. Being the exclusive source of dTMP, investigators have concluded that TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head, and neck. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 36 kDa

Observed MW: 36 kDa

UniProt: P04818

Pathways: Mitotic G1-G1/S Phases