Recombinant Vitamin D Receptor anticorps
Aperçu rapide pour Recombinant Vitamin D Receptor anticorps (ABIN7828672)
Antigène
Voir toutes Vitamin D Receptor (VDR) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant Vitamin D Receptor Monoclonal Antibody
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Purification
- Protein A purified
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:1000-1:3000,IP 1:50-1:100
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- Vitamin D Receptor (VDR)
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Autre désignation
- Vitamin D Receptor
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Classe de substances
- Chemical
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Sujet
- NR1I,nuclear receptor subfamily,PPP1R,member,VDR,NR1I1,PPP1R163,group I,member 1,nuclear receptor subfamily 1,vitamin D receptor,This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 48 kDa
Observed MW: 48 kDa
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UniProt
- P11473
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
Antigène
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