Recombinant VWF anticorps

N° du produit ABIN7828674

Cet anticorps anti-VWF Monoclonal Lapin (Clone A683) (ABIN7828674) détecte spécifiquement VWF dans IHC et WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant VWF anticorps (ABIN7828674)

Antigène: VWF (Von Willebrand Factor (VWF))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp VWF est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: A683

Détail du produit anti-VWF anticorps

Fonction: Recombinant Von Willebrand Factor Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Von Willebrand Factor fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:5000-1:10000,IHC 1:100-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur VWF

Antigène: VWF (Von Willebrand Factor (VWF))

Autre désignation: Von Willebrand Factor

Sujet: F8VWF,VWD,von Willebrand factor,von Willebrand antigen II,Vwf,VWF (Von Willebrand factor) is a multimeric plasma glycoprotein that promotes adhesion of platelets to sites of vascular injury. Mature circulating VWF is made up of disulfide-bonded multimers that are in a complex with factor VIII. VWF is stored in secretory Weibel-Palade bodies in endothelial cells. It is synthesized as a large precursor protein and undergoes extensive posttranslational modifications including dimerization in the endoplasmic reticulum followed by cleavage of the pro-peptide and multimerization in the Golgi apparatus. VWF is important in hemostasis, and genetic defects in the structure and modification of VWF can cause von Willebrand disease (VWD), the most common congenital bleeding disorder in humans. Alternatively, increased levels of VWF have been shown to be involved in acute coronary thrombosis and are a clinical risk marker for atherosclerosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 309 kDa

Observed MW: 309 kDa

UniProt: Q8CIZ8