Recombinant WT1 anticorps

N° du produit ABIN7828676

L’anticorps anti-WT1 Monoclonal Lapin est utilisé pour la détection de WT1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour IHC et WB.

Aperçu rapide pour Recombinant WT1 anticorps (ABIN7828676)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: A742

Détail du produit anti-WT1 anticorps

Fonction: Recombinant WT1 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:2000-1:10000,IHC 1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: WT1

Sujet: AWT,FWT,NPHS,EWS-WT,WIT,WT1,AWT1,EWS-WT1,GUD,NPHS4,WAGR,WIT-2,WT33,FWT1,Wilms Tumor,Wilms tumor 1,Wilms' tumor gene,Wilms tumor protein,Wilms' tumor protein,WIT 2,WIT2,WT,WT 1,WIT 2, WT 1,AWT1,FWT1,GUD,NPHS4,WAGR,Wilms tumor 1,Wilms Tumor,Wilms tumor protein,Wilms' tumor gene,Wilms' tumor protein,WIT2,WT,WT1,WT1,WT33,Wilms' Tumor protein (WT1) is a transcription factor named from Wilms' Tumor 1, an embryonal malignancy of the kidneys that is caused by mutations in the WT1 gene. It is highly important in development, particularly of the genitourinary system, and mutations and dysregulation of expression of WT1 result in a variety of syndromes affecting the genitourinary system and other tissues.WT1 has a myriad of biological functions and a host of interacting partners and target genes. It can behave as a transcriptional activator, or a repressor, and can act as an oncogene or a tumor suppressor. It exerts influence over the epigenetic landscape, and also has post translational influence of gene expression through RNA interactions. The diverse biological roles of WT1 have been attributed to the existence of multiple isoforms and post translation modifications of the protein. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 49 kDa

Observed MW: 52 kDa The actual band is not consistent with the expectation.

UniProt: P19544

Pathways: Tube Formation