Recombinant ZNF259 anticorps

N° du produit ABIN7828682

L’anticorps anti-ZNF259 Monoclonal Lapin est utilisé pour la détection de ZNF259 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Recombinant ZNF259 anticorps (ABIN7828682)

Antigène: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ZNF259 est non-conjugé

Application: Western Blotting (WB)

Clone: A747

Détail du produit anti-ZNF259 anticorps

Fonction: Recombinant ZPR1 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur ZNF259

Antigène: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Autre désignation: ZPR1

Sujet: ZPR,MGC,Zinc finger protein,Zinc finger protein ZPR,ZNF,ZPR1,ZNF259,MGC110983,Zinc finger protein 259,Zinc finger protein ZPR1,ZNF 259,The zinc finger protein ZPR1 (ZNF259) binds to epidermal growth factor receptor (EGFR) and is localized to both cytoplasm and nucleus. The zinc fingers found in ZPR1 and the tyrosine kinase domain of EGFR mediate the interaction between ZPR1 and the receptor (1). ZPR1 translocates from the cytoplasm to nucleus following mitogen (i.e. EGF) stimulation (2,3). ZPR1 also interacts with translation elongation factor eEF1A in vivo following EGF treatment (3). The interaction between the zinc finger protein and elongation factor is important for cell proliferation. Cells lacking ZPR1 exhibit abnormal nucleolar function, suggesting that ZPR1 is required for cell viability and nucleolar function in dividing cells (3). ZPR1 knockout mice exhibit significant neurodegeneration, and reduced or altered expression of ZPR1 may contribute to spinal muscular atrophy, a disorder characterized by degeneration of spinal cord neurons (4). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 51 kDa

Observed MW: 53 kDa The actual band is not consistent with the expectation.

UniProt: O75312