CD51 anticorps

N° du produit ABIN7828788

Cet anticorps anti-CD51 Monoclonal Rat (Clone RMV-7) (ABIN7828788) détecte spécifiquement CD51 dans FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour CD51 anticorps (ABIN7828788)

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD51 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: RMV-7

Détail du produit anti-CD51 anticorps

Fonction: Purified Anti-Mouse CD51 Antibody[RMV-7]

Purification: >98%, Protein A/G purified

Pureté: >98 %

Immunogène: Recombinant MouseCD51 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: FCM 2 μg/mL(0.5x106-1x106 cells)

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CD51

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: CD51

Sujet: Integrin alpha-V;Integrin αV chain;Vitronectin Receptor;αV integrin;Itgav;vitronectin R;integrin &alpha-V-V,CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αv integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P43406

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex