LY75/DEC-205 anticorps

N° du produit ABIN7828842

Cet anticorps anti-LY75/DEC-205 Monoclonal Rat (Clone NLDC-145) (ABIN7828842) détecte spécifiquement LY75/DEC-205 dans FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour LY75/DEC-205 anticorps (ABIN7828842)

Antigène: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp LY75/DEC-205 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: NLDC-145

Détail du produit anti-LY75/DEC-205 anticorps

Fonction: AF/LE Purified Anti-Mouse CD205 Antibody[NLDC-145]

Purification: >98%, Protein A/G purified

Pureté: >98 %

Immunogène: Recombinant Mouse CD205 protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application: FCM 2 μg/mL(0.5x106-1x106 cells)

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Agent conservateur: Without preservative

Conseil sur la manipulation: This preparation contains no preservatives, thus it should be handled under aseptic conditions

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Date de péremption: 12 months

Détails sur LY75/DEC-205

Antigène: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Autre désignation: CD205

Sujet: Cd205,Ly75,DEC-205,Ly-75,CD205, also known as DEC-205, is a 205 kD integral membrane protein homologous to the macrophage mannose receptor. It is a type I cell surface protein that belong to the C-type lectin family. CD205 is expressed at high levels by dendritic cells and thymic epithelial cells. It is also expressed by a number of other cell types, such as B lymphocytes, macrophages, Langerhans cells, bone marrow stromal cells, granulocytes, epithelial cells of pulmonary airways, and the capillaries of the brain. CD205 is a novel endocytic receptor used by dendritic cells and thymic epithelial cells to direct captured antigens from the extracellular space to specialized antigen processing. It mediates antigen uptake and presentation and cross-presentation to T cells. It has been reported that CD205 acts as a recognition receptor for dying cells, potentially provides an important pathway for the uptake of self-antigen in the intrathymic environment, and is involved in peripheral tolerance. Antibody-mediated antigen-targeting via the DEC-205 receptor increases the efficiency of vaccination for T cell immunity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q60767