GRPR anticorps
Aperçu rapide pour GRPR anticorps (ABIN7829616)
Antigène
Voir toutes GRPR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-GRPR antibody(3B12), Rabbit mAb
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG
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Indications d'application
- Flow Cyt 1/100
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
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Date de péremption
- 12 months
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- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
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Autre désignation
- GRPR
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Sujet
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
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UniProt
- P30550
Antigène
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