Recombinant CXCR6 anticorps

N° du produit ABIN7829682

Cet anticorps anti-CXCR6 Chimeric Human (Clone 2B3) (ABIN7829682) détecte spécifiquement CXCR6 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant CXCR6 anticorps (ABIN7829682)

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Type d'anticorp: Recombinant Antibody

Fragment: Fc fragment

Reactivité: Humain

Hôte: Human, Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CXCR6 est non-conjugé

Application: ELISA

Clone: 2B3

Détail du produit anti-CXCR6 anticorps

Fonction: Anti-CXCR6 antibody(2B3), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: ELISA 1/5000-10000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Date de péremption: 12 months

Détails sur CXCR6

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Autre désignation: CXCR6

Sujet: The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]

UniProt: O00574