IL-10 anticorps

N° du produit ABIN7829687

L’anticorps anti-IL-10 Monoclonal Lapin est utilisé pour la détection de IL-10 dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour IL-10 anticorps (ABIN7829687)

Antigène: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-10 est non-conjugé

Application: ELISA

Clone: 9E11

Détail du produit anti-IL-10 anticorps

Fonction: Anti-IL10 antibody(9E11), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Information d'application

Indications d'application: ELISA 1/5000-10000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Date de péremption: 12 months

Détails sur IL-10

Antigène: IL-10 (IL10) (Interleukin 10 (IL10))

Autre désignation: IL10

Sujet: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints