Nitrotyrosine anticorps

N° du produit ABIN7833437

Cet anticorps anti-Nitrotyrosine Monoclonal Souris (Clone EM-30) (ABIN7833437) détecte spécifiquement Nitrotyrosine dans WB, IHC (fro) et IHC (p).

Aperçu rapide pour Nitrotyrosine anticorps (ABIN7833437)

Antigène: Nitrotyrosine

Reactivité: Veuillez nous consulter SVP

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Nitrotyrosine est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EM-30

Détail du produit anti-Nitrotyrosine anticorps

Fonction: Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30)

Réactivité croisée (Details): Nitrotyrosine

Immunogène: NO2-Tyr-CH2-Thyroglobulin

Isotype: IgG1

Information d'application

Indications d'application: (IHC) paraffin: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia. (IHC) frozen sections: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia. (WB): positive control: NO2-BSA, NO2-HSA.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Immunoglobulin purified on Protein A.

Conseil sur la manipulation: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube,Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Détails sur Nitrotyrosine

Antigène: Nitrotyrosine

Classe de substances: Chemical

Sujet:

Background: Nitrotyrosine can be detected in proteins from a variety of tissues, usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.

Additional information: This antibody detects nitrotyrosine group in biological material, It can be used as a marker for peroxynitrite formation in particular tissues