TTR anticorps

N° du produit ABIN7833608

Cet anticorps anti-TTR Monoclonal Souris (ABIN7833608) détecte spécifiquement TTR dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TTR anticorps (ABIN7833608)

Antigène: TTR (Transthyretin (TTR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TTR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-TTR anticorps

Fonction: Anti-Transthyretin 56-61, amyloid specific (mouse monoclonal)

Réactivité croisée (Details): Human Transthyretin Amyloids
Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Purification: Affinity purified

Immunogène: Recombinant protein corresponding to the Human wild type Transthyretin. GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE The epitope has been mapped to residue 56-61

Isotype: IgG1

Information d'application

Indications d'application: 1:1000 (ELISA), 1:500 (IHC), 1:1000 (WB)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 μL sterile water to reconstitute to 1 mg/mL

Buffer: Affinity purified in PBS pH 7.4.

Conseil sur la manipulation: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Stock: 4 °C

Stockage commentaire: Store lyophilized/reconstituted at 4°C, Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Détails sur TTR

Antigène: TTR (Transthyretin (TTR))

Autre désignation: Transthyretin 56-61

Sujet: Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. The wild type form of TTR is associated with a late onset amyloidosis denoted senile systemic amyloidosis, affecting around 10 % of the population above 80 years of age with depositions mainly found in the heart.Monoclonal IgG1 antibody. Amyloid specific for human Transthyretin. Detects the C-terminal fragment 49-127 frequently formed in vivo.

Poids moléculaire: 155

Pathways: Hormone Transport