CCR5 anticorps (AA 201-300)

N° du produit ABIN741375

Cité dans 1 publication. Cet anticorps anti-CCR5 Polyclonal Lapin (ABIN741375) détecte spécifiquement CCR5 dans WB, ELISA, FACS, IHC (p), IHC (fro), IF (cc) et IF (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CCR5 anticorps (AA 201-300) (ABIN741375)

Antigène: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR5 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CCR5 anticorps

Épitope: AA 201-300

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CCR-5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CCR5 (ABIN741375)

Ochoa-Callejero, Pérez-Martínez, Rubio-Mediavilla, Oteo, Martínez, Blanco: "Maraviroc, a CCR5 antagonist, prevents development of hepatocellular carcinoma in a mouse model." dans: PLoS ONE, Vol. 8, Issue 1, pp. e53992, (2013) (PubMed).

Détails sur CCR5

Antigène: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Autre désignation: CCR5/CD195

Sujet:

Synonyms: CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, C-C chemokine receptor type 5, C-C CKR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor

Background: Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

ID gène: 1234

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size