CD163 anticorps (AA 1001-1121)

N° du produit ABIN741570

Cet anticorps anti-CD163 est un anticorps Lapin Polyclonal détectant CD163 dans WB, FACS, ELISA, IHC (p), ICC, IHC (fro), IF (cc) et IF (p). Adapté pour Humain, Souris, Rat, Porc et Chien. Ce Primary Antibody a été cité dans 27+ publications.

Aperçu rapide pour CD163 anticorps (AA 1001-1121) (ABIN741570)

Antigène: CD163

Reactivité: Humain, Souris, Rat, Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD163 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CD163 anticorps

Épitope: AA 1001-1121

Réactivité croisée: Chien, Humain, Souris, Porc, Rat

Homologie: Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CD163/M130

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CD163 (ABIN741570)

Riuzzi, Beccafico, Sagheddu, Chiappalupi, Giambanco, Bereshchenko, Riccardi, Sorci, Donato: "Levels of S100B protein drive the reparative process in acute muscle injury and muscular dystrophy." dans: Scientific reports, Vol. 7, Issue 1, pp. 12537, (2019) (PubMed).

Kobori, Hamasaki, Kitaura, Yamazaki, Nishinaka, Niwa, Nakao, Wake, Mori, Yoshino, Nishibori, Takahashi: "Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis." dans: Frontiers in immunology, Vol. 9, pp. 334, (2019) (PubMed).

Yin, Chang, Xu: "Expressions Profiles of the Proteins Associated with Carbohydrate Metabolism in Rat Liver Regeneration." dans: BioMed research international, Vol. 2017, pp. 8428926, (2018) (PubMed).

Chen, Zhang, Wang, Chen, Yan, Zhang, Zhang: "Peptide-modified chitosan hydrogels promote skin wound healing by enhancing wound angiogenesis and inhibiting inflammation." dans: American journal of translational research, Vol. 9, Issue 5, pp. 2352-2362, (2017) (PubMed).

Bobi, Solanes, Fernández-Jiménez, Galán-Arriola, Dantas, Fernández-Friera, Gálvez-Montón, Rigol-Monzó, Agüero, Ramírez, Roqué, Bayés-Genís, Sánchez-González, García-Álvarez, Sabaté, Roura, Ibáñez et al.: "Intracoronary Administration of Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells Improves Myocardial Perfusion But Not Left Ventricle Function, in a Translational Model of Acute Myocardial ..." dans: Journal of the American Heart Association, Vol. 6, Issue 5, (2017) (PubMed).

Gerzanich, Makar, Guda, Kwon, Stokum, Woo, Ivanova, Ivanov, Mehta, Morris, Bryan, Bever, Simard: "Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis." dans: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 177, (2017) (PubMed).

Lee, Liao, Wang, Yang, Luo, Varki, Qiu, Ren, Fu, Feng: "Preventive Inhibition of Liver Tumorigenesis by Systemic Activation of Innate Immune Functions." dans: Cell reports, Vol. 21, Issue 7, pp. 1870-1882, (2017) (PubMed).

Dinulovic, Furrer, Di Fulvio, Ferry, Beer, Handschin: "PGC-1α modulates necrosis, inflammatory response, and fibrotic tissue formation in injured skeletal muscle." dans: Skeletal muscle, Vol. 6, pp. 38, (2017) (PubMed).

Tauchi, Tanaka, Kumamoto, Tokumoto, Sakimura, Sakurai, Kimura, Toyokawa, Amano, Kubo, Muguruma, Yashiro, Maeda, Ohira, Hirakawa: "Tumor-associated macrophages induce capillary morphogenesis of lymphatic endothelial cells derived from human gastric cancer." dans: Cancer science, Vol. 107, Issue 8, pp. 1101-9, (2017) (PubMed).

Jacobsen, Mentzel, Olesen, Huby, Jørgensen, Barrès, Fredholm, Simar: "Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity." dans: Journal of diabetes research, Vol. 2016, pp. 8539057, (2016) (PubMed).

Kugo, Zaima, Tanaka, Mouri, Yanagimoto, Hayamizu, Hashimoto, Sasaki, Sano, Yata, Urano, Setou, Unno, Moriyama: "Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm." dans: Scientific reports, Vol. 6, pp. 31268, (2016) (PubMed).

Drel, Tan, Barnes, Gorin, Lee, Wagner: "Centrality of bone marrow in the severity of gadolinium-based contrast-induced systemic fibrosis." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 9, pp. 3026-38, (2016) (PubMed).

Das, Singh, Majid, Sherman, Mukhopadhyay, Wright, Martin, Dunn, Baker: "Syndesome Therapeutics for Enhancing Diabetic Wound Healing." dans: Advanced healthcare materials, Vol. 5, Issue 17, pp. 2248-60, (2016) (PubMed).

Chen, Shi, Zhang, Chen, Wang, Zhang, Tian, Yan, Li, Zhong, Xing, Zhang, Zhang: "Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing." dans: Scientific reports, Vol. 5, pp. 18104, (2016) (PubMed).

Fernandez-Bustamante, Agazio, Wilson, Elkins, Domaleski, He, Baer, Moss, Wischmeyer, Repine et al.: "Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in ..." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0130764, (2016) (PubMed).

Tepeköylü, Lobenwein, Blunder, Kozaryn, Dietl, Ritschl, Pechriggl, Blumer, Bitsche, Schistek, Kotsch, Fritsch, Grimm, Holfeld: "Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice†." dans: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 47, Issue 3, pp. e80-90, (2015) (PubMed).

Ge, Li, Jiang, You, Liu, Zhong, Huang, Xing: "Integration of nondegradable polystyrene and degradable gelatin in a core-sheath nanofibrous patch for pelvic reconstruction." dans: International journal of nanomedicine, Vol. 10, pp. 3193-201, (2015) (PubMed).

Franken, Klein, Spasova, Elsukova, Wiedwald, Welz, Knolle, Farle, Limmer, Kurts: "Splenic red pulp macrophages are intrinsically superparamagnetic and contaminate magnetic cell isolates." dans: Scientific reports, Vol. 5, pp. 12940, (2015) (PubMed).

Détails sur CD163

Antigène: CD163

Autre désignation: Cd163/M130

Sujet:

Synonyms: M13, MM13, Scavenger receptor cysteine-rich type 1 protein M13, Hemoglobin scavenger receptor, CD163, M130

Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.

ID gène: 9332

UniProt: Q86VB7