SLAMF7 anticorps (AA 51-160) (FITC)

N° du produit ABIN741832

Cet anticorps Lapin Polyclonal détecte spécifiquement SLAMF7 dans WB et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SLAMF7 anticorps (AA 51-160) (FITC) (ABIN741832)

Antigène: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLAMF7 est conjugé à/à la FITC

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-SLAMF7 anticorps (FITC)

Épitope: AA 51-160

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLAMF7

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SLAMF7

Antigène: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Autre désignation: Slamf7/Cd319/Cs1

Sujet:

Synonyms: 19A, 19A24 protein, CD 319, CD2 like receptor activating cytotoxic cells, CD2 subset 1, CD319, CD319 antigen, CRACC, CS1, Membrane protein FOAP 12, Novel Ly9, Novel LY9 lymphocyte antigen 9 like protein, Protein 19A, SLAM family member 7, SLAMF 7.

Background: SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.

UniProt: Q9NQ25