D-Dimer anticorps
Aperçu rapide pour D-Dimer anticorps (ABIN7849757)
Antigène
Voir toutes D-Dimer AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Monoclonal Anti-D-dimer (Detection Ab)
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Specificité
- It specifically recognize human D-dimer antigen, and does not cross react with BSA, but has week cross-reactivity withfibrinogen.
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Attributs du produit
- This antibody may be used as in antibody pair experiments such as ELISA.
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Purification
- Protein A or G purified
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Pureté
- >95 % by HPLC & SDS-PAGE
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Immunogène
- Human D-dimer protein.
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.01 M PBS ( pH 7.4) without preservative.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freeze and thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
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Date de péremption
- 12 months
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- D-Dimer
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Sujet
- D-dimer is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrin protein. The D-dimer antigen is a unique marker of fibrin degradation that is formed by the sequential action of 3 enzymes: thrombin, factor XIIIa, and plasmin. Its concentration may be determined by a blood test to help diagnose thrombosis. Since its introduction in the 1990s, it has become an important test performed in patients suspected of thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation.
Antigène
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