LCN2
Reactivité: Humain
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Buffer
0.01 M PBS ( pH 7.4) without preservative.
Agent conservateur
Without preservative
Conseil sur la manipulation
Avoid repeated freeze and thaw cycles.
Stock
-20 °C
Stockage commentaire
Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Date de péremption
12 months
Antigène
Lipocalin 2 (LCN2)
Autre désignation
NGAL
Sujet
Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.