ICOS anticorps (AA 51-150) (HRP)
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- Antigène Voir toutes ICOS Anticorps
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
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Épitope
- AA 51-150
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ICOS est conjugé à/à la HRP
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This antibody may also have a secondary cross-reactivity with AP-1 complex-associated regulatory protein due to a 77 % non-contiguous sequence similarity in the corresponding immunogen region.
- Réactivité croisée
- Humain
- Homologie
- Mouse,Rat,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ICOS
- Isotype
- IgG
- Top Product
- Discover our top product ICOS Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Autre désignation
- ICOS/CD278 (ICOS Produits)
- Synonymes
- anticorps ICOS, anticorps AILIM, anticorps CCLP, anticorps CRP-1, anticorps H4, anticorps Ly115, anticorps CD278, anticorps CVID1, anticorps Ailim, anticorps inducible T-cell costimulator, anticorps inducible T cell co-stimulator, anticorps inducible T-cell co-stimulator, anticorps ICOS, anticorps LOC100232284, anticorps Icos
- Sujet
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Synonyms: AILIM, CD278, CVID1, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, ICOS
Background: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
- ID gène
- 29851
- UniProt
- Q9Y6W8
- Pathways
- Cancer Immune Checkpoints
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