Recombinant ACE2 anticorps (AA 705-805)

N° du produit ABIN7857675

L’anticorps anti-ACE2 Monoclonal Lapin est utilisé pour la détection de ACE2 dans des échantillons de Humain, Cobaye et Hamster. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour Recombinant ACE2 anticorps (AA 705-805) (ABIN7857675)

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Cobaye, Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ACE2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: ACE2-8748R

Détail du produit anti-ACE2 anticorps

Épitope: AA 705-805

Expression System: CHO Cells

Fonction: Recombinant ACE2 / Angiotensin I Converting Enzyme 2 Antibody

Specificité: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Recombinant fragment (around aa705-805) of human ACE2 (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur ACE2

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Autre désignation: ACE2

Sujet:

ACE related carboxypeptidase, ACE2, ACEH, Angiotensin converting enzyme 2, Angiotensin converting enzyme like protein, Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2, Angiotensin-converting enzyme homolog, EC 3.4.17, DKFZP434A014, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2

Human heart, kidney, testis or small intestine.

Poids moléculaire: 92kDa

ID gène: 59272, 178098

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour