Recombinant HSPH1 anticorps (C-Term)

N° du produit ABIN7865495

Cet anticorps Souris Monoclonal détecte spécifiquement HSPH1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant HSPH1 anticorps (C-Term) (ABIN7865495)

Antigène: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSPH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: R58F12

Détail du produit anti-HSPH1 anticorps

Épitope: C-Term

Expression System: CHO Cells

Fonction: Recombinant Heat Shock Protein 105 kDa / HSP105 (Basaloid Skin Tumor Marker) Antibody

Specificité: Heat shock protein (HSP) 105 exists as two isoforms, alpha and beta which belong to the HSP105/HSP110 protein family. HSP105 acts as both a chaperone to prevent thermal aggregation of proteins and as a regulator of mammalian cells. The HSP105 isoforms are found in the cytoplasm but not in the nucleoli under non-stressed and stressed conditions. In rodents, HSP105 isoforms are moderately expressed in the adrenal glands, spleen, liver and heart and both are markedly increased after heat shock. In the testis, HSP105 is specifically localized in the cytoplasm of germ cells and may translocate to the nucleus after heat shock. The most abundant expression occurs in the brain with nuclear and cytoplasmic expression in nearly all neurones, oligodendrocytes, microglia and astrocytes. Increased expression during embryogenesis suggests that HSP105 may have an important role during mouse embryo development.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Prokaryotic recombinant protein of 31 kD corresponding to the C-terminus of the heat shock protein 105 molecule

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur HSPH1

Antigène: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Autre désignation: Heat Shock Protein 105 kDa

Sujet:

HSP105, HSP110, KIAA0201, HSPH1, Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, Heat shock protein family H member 1

Human brain or testis.

Poids moléculaire: 105kDa

ID gène: 10808

UniProt: Q92598