Recombinant SPARC anticorps (C-Term)
Aperçu rapide pour Recombinant SPARC anticorps (C-Term) (ABIN7857698)
Antigène
Voir toutes SPARC AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Expression System
- CHO Cells
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Fonction
- Recombinant SPARC / Osteonectin / O-Nectin Antibody
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Specificité
- Osteonectin (ON), also known as BM-40 or SPARC (secreted protein, acidic and rich in cysteine) is a multifunctional glycoprotein (32.5 kD) involved with tissue mineralization as well as extracellular matrix modelling. It is the most abundant glycoprotein secreted by human osteoblasts in developing bone and odontoblasts of developing teeth. ON mRNA and protein have been detected in non-mineralized tissues such as steroid-producing cells of the adrenal glands, suprabasal layers of the epidermis, glomeruli in the kidney, bronchi of the lung, megakaryocytes and large vessels. This organ-specific distribution in non-mineralized tissues suggests a role during human development.
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Purification
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogène
- Prokaryotic recombinant protein corresponding to a portion of the C-terminus of the human osteonectin molecule
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
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Autre désignation
- SPARC
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Sujet
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Basement membrane protein 40, BM40, Cysteine rich protein, OI17, ON, Osteonectin, Secreted acidic cystein rich glycoprotein, Secreted protein acidic and cysteine rich, Secreted protein acidic and rich in cysteine (SPARC)
Human placenta, lymph node or spleen. JEG3, A-375 or A549 cell lysates.
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Poids moléculaire
- 38kDa
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ID gène
- 6678, 111779, 708558
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UniProt
- P09486
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Pathways
- Autophagy
Antigène
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