Recombinant SV2A anticorps (Cytoplasmic Domain, N-Term)

N° du produit ABIN7865492

Cet anticorps anti-SV2A Monoclonal Souris (Clone r15E11) (ABIN7865492) détecte spécifiquement SV2A dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant SV2A anticorps (Cytoplasmic Domain, N-Term) (ABIN7865492)

Antigène: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SV2A est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: R15E11

Détail du produit anti-SV2A anticorps

Épitope: Cytoplasmic Domain, N-Term

Expression System: CHO Cells

Fonction: Recombinant Synaptic Vesicle Protein 2 (SV2) (Marker of Neuroendocrine Cells) Antibody

Specificité: Synaptic vesicle protein 2 (SV2) is an integral membrane glycoprotein. It is required for normal neurotransmission and may play a role in the regulation of calcium-stimulated exocytosis. SV2 exists in three forms, SV2A, SV2B and SV2C, each containing 12 transmembrane spanning regions. SV2 proteins are among the most abundant and conserved components of synaptic vesicles in vertebrates. They are present on all small synaptic vesicles independent of transmitter type. SV2A and SV2B are widely distributed in the nervous system, whereas SV2C is only observed in a small number of neurons in a few areas of the brain. SV2A is expressed at the highest levels in subcortical regions, whereas the highest level of expression of SV2B is in the cortex and hippocampus. SV2 is expressed on secretory vesicles of neuroendocrine cells in the GI tract, pancreas, anterior pituitary gland, thyroid, parathyroid and adrenal medulla and also in exocrine chief cells of gastric mucosa.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Prokaryotic recombinant protein corresponding to the N-terminal cytoplasmic domain of the human synaptic vesicle 2A molecule which shares some regions of homology with the SV2B molecule

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur SV2A

Antigène: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Autre désignation: Synaptic Vesicle Protein 2

Sujet:

KIAA0736 | PSEC0174 | SV2A | Synaptic vesicle glycoprotein 2A

Human brain.

Poids moléculaire: 93kDa

ID gène: 9900

UniProt: Q7L0J3