Recombinant ABCC3 anticorps
Aperçu rapide pour Recombinant ABCC3 anticorps (ABIN7857729)
Antigène
Voir toutes ABCC3 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Expression System
- CHO Cells
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Fonction
- Recombinant MRP3 (Multidrug Resistance-Associated Protein 3) Antibody
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Specificité
- The human multidrug resistance-associated protein (MRP) gene family contains at least 6 members designated MRP-1 to 6. MRP3 is a 190 to 200 kD integral membrane protein which is an organic anion transporter effective in transporting chemotherapeutic drugs such as MTX, etoposide and teniposide. Northern blotting of various human tissues has indicated MRP3 to be expressed in liver, colon, pancreas and at lower levels in the kidney. In liver, MRP3 is localized to the basolateral membrane of hepatocytes and is not associated with the canalicular membrane. MRP3 is also thought to play a role in bile production and secretion in the liver.
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Purification
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogène
- Recombinant prokaryotic fusion protein corresponding to a region of the cytoplasmic domains between transmembrane domains 11 and 12 of the MRP3 molecule
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Isotype
- IgG2b, kappa
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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 815-957) antibody
ABCC3 Reactivité: Humain IHC Hôte: Souris Monoclonal ABCC3-2971 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 899-925) antibodyABCC3 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB22384 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 849-963) antibodyABCC3 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1A2F6 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (Middle Region) antibodyABCC3 Reactivité: Humain, Rat, Chien, Cobaye, Cheval, Porc WB Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 1291-1523) antibodyABCC3 Reactivité: Humain WB, ELISA, IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (Internal Region) antibodyABCC3 Reactivité: Humain, Rat WB, ELISA, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 906-933), (Middle Region) antibodyABCC3 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 827-953) antibodyABCC3 Reactivité: Humain ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 684-733) antibodyABCC3 Reactivité: Humain, Chien, Cobaye WB Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) antibodyABCC3 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))
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Autre désignation
- MRP3
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Sujet
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ABC31, ATP-binding cassette sub-family C member 3 (ABCC3), Canalicular multispecific organic anion transporter 2 (CMOAT2), MLP2, MOATD, Multi-specific organic anion transporter D, Multidrug resistance-associated protein 3
Human bowel, pancreas or adrenal gland.
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Poids moléculaire
- 169/137/55/32/65kDa
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ID gène
- 8714, 463421
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UniProt
- O15438
Antigène
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