Recombinant CD151 anticorps

N° du produit ABIN7863813

L’anticorps anti-CD151 Monoclonal Lapin est utilisé pour la détection de CD151 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant CD151 anticorps (ABIN7863813)

Antigène: CD151

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD151 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: CD151-9297R

Détail du produit anti-CD151 anticorps

Expression System: CHO Cells

Fonction: Recombinant CD151 Antibody

Specificité: CD151 is involved in a wide variety of cell biological processes, including cell adhesion and the transport of integrins via vesicles. The human CD151 gene maps to chromosome 11p15.5 and encodes a 253 amino acid protein, which belongs to the tetraspan (4TM) superfamily. CD151 can associate with several integrin chains including ≤1, ≤3, ≤4, ±2, ±3, ±5 and ±6 integrins. CD151 may provide a framework for the spatial organization of both type I and type II hemidesmosomes, which are specialized junctional complexes that function as cell attachment sites for binding to basement membranes. CD151 RNA transcript (1.6 kb) can be detected in MO7e cells, bone marrow stromal cells, C11 endothelial cells, HUVEC and several myeloid leukemia cell lines, however, no transcript is detected in brain and the lymphoblastoid cell lines MOLT-4 and BALM-1. Leu 149-Glu 213 of CD151 is the interface through which Integrin ±3/≤1 can bind. CD151 can enhance cell motility, invasion and metastasis of cancer cells in a focal adhesion kinase dependent manner.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Recombinant full-length human CD151 protein

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CD151

Antigène: CD151

Autre désignation: CD151

Sujet:

GP27, hemidesmosomal tetraspanin CD151, Membrane glycoprotein SFA-1, MER2, Platelet endothelial tetraspan antigen 3 (PETA3), platelet surface glycoprotein gp27, Platelet-endothelial cell tetraspan antigen 3, Platelet-endothelial tetraspan antigen 3, RAPH, Red blood cell antigen MER2, SFA1, Tetraspanin-24 (TSPAN24)

Human tonsil or spleen.

Poids moléculaire: 28-32kDa

ID gène: 977, 654379

UniProt: P48509