Recombinant CRYAB anticorps
Aperçu rapide pour Recombinant CRYAB anticorps (ABIN7865474)
Antigène
Voir toutes CRYAB AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Expression System
- CHO Cells
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Fonction
- Recombinant Crystallin Alpha B / CRYAB (Marker of Metaplastic Carcinoma) Antibody
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Specificité
- Alpha B crystallin is a lens protein which has some homology with the small heat shock proteins. It is expressed in tissues such as skeletal muscle, cardiac muscle, smooth muscle, renal tubular epithelium, Schwann cells, glial cells, thyroid epithelium, colonic epithelium and stratified squamous epithelium. Alpha B crystallin is also reported to be found in ubiquitinated intermediate filament inclusion bodies, such as Lewy bodies (neurofilaments), Rosenthal fibres (glial filaments) and Mallory bodies (cytokeratins). Alpha B crystallin is rarely found in neurofibrillary tangles. The role of Alpha B crystallin in these inclusion bodies is unknown, however, it may function as an accessory protein for intermediate filament aggregation.
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Purification
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogène
- Synthetic peptide hemocyanin conjugate. The peptide corresponds to human alpha B crystallin amino acids 1 to 10.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CRYAB (Crystallin, alpha B (CRYAB))
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Autre désignation
- Crystallin Alpha B
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Sujet
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AACRYA, Alpha B crystallin, Alpha-crystallin B chain, CRYA2, CTTP2, Heat shock 20 kD like protein, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY REN 27, Rosenthal fiber component
Human heart, kidney or brain.
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Poids moléculaire
- Predicted: 20kDa, Observed: 22-30kDa
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ID gène
- 1410, 53454
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UniProt
- P02511
Antigène
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