Recombinant HSP90 anticorps

N° du produit ABIN7857794

Cet anticorps Souris Monoclonal détecte spécifiquement HSP90 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant HSP90 anticorps (ABIN7857794)

Antigène: HSP90 (Heat Shock Protein 90 (HSP90))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSP90 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: R2B4

Détail du produit anti-HSP90 anticorps

Expression System: CHO Cells

Fonction: Recombinant Heat Shock 27kDa Protein 1 Antibody

Specificité: HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50 % homology with low molecular weight Drosophila HSPs and mammalian ±-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Prokaryotic recombinant protein corresponding to the full length human heat shock protein 27 molecule

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur HSP90

Antigène: HSP90 (Heat Shock Protein 90 (HSP90))

Autre désignation: Heat Shock Protein 1

Sujet:

Heat shock 27 kDa protein, Estrogen-regulated 24 kDa protein, Heat shock 25 kDa protein 1, Heat shock 28 kDa protein 1, Heat shock protein beta-1, HMN2B, Hsp25, Hsp28, HspB1, Stress-responsive protein 27 (SRP27)

~50 % of breast carcinomas are positive for hsp27 especially those that are ER and/or PgR positive.

Poids moléculaire: 27kDa

ID gène: 3315, 520973

UniProt: P04792

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals