Recombinant Cytokeratin 13 anticorps

N° du produit ABIN7857802

Cet anticorps anti-Cytokeratin 13 Monoclonal Souris (Clone rKRT13-9623) (ABIN7857802) détecte spécifiquement Cytokeratin 13 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Cytokeratin 13 anticorps (ABIN7857802)

Antigène: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 13 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RKRT13-9623

Détail du produit anti-Cytokeratin 13 anticorps

Expression System: CHO Cells

Fonction: Recombinant Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker) Antibody

Specificité: Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs)that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with Cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: esophageal keratins of rabbit origin

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Cytokeratin 13

Antigène: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Autre désignation: Cytokeratin 13

Sujet:

CK13, Cytokeratin-13, Keratin Type I Cytoskeletal 13, Keratin-13, KRT13, Type I Cytoskeletal 13, WSN2

HeLa or A431 cells. Skin or Squamous cell carcinoma

Poids moléculaire: 52kDa

ID gène: 3860, 654550

UniProt: P13646