Laminin gamma 1 anticorps

N° du produit ABIN7857806

Cet anticorps Lapin Monoclonal détecte spécifiquement Laminin gamma 1 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Laminin gamma 1 anticorps (ABIN7857806)

Antigène: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Laminin gamma 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: LAMC1-13970R

Détail du produit anti-Laminin gamma 1 anticorps

Expression System: CHO Cells

Fonction: Laminin, gamma 1 (LAMC1) Antibody

Specificité: Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. This MAb reacts with laminin B2/1 chain of ~210 kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Recombinant human full-length LAMC1 protein

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Laminin gamma 1

Antigène: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Autre désignation: Laminin, gamma 1

Sujet:

LAMB2, LAMC1, Laminin B2 chain, Laminin gamma 1, Laminin gamma 1 chain

Normal colon or carcinomas.

Poids moléculaire: 210kDa

ID gène: 3915

UniProt: P11047