Recombinant P-Cadherin anticorps

N° du produit ABIN7857818

Cet anticorps Souris Monoclonal détecte spécifiquement P-Cadherin dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant P-Cadherin anticorps (ABIN7857818)

Antigène: P-Cadherin (CDH3)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: R56C1

Détail du produit anti-P-Cadherin anticorps

Expression System: CHO Cells

Fonction: Recombinant P-Cadherin (CDH3) (Basal Epithelial Cell Marker) Antibody

Specificité: Recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Prokaryotic recombinant protein corresponding to a region of the external domain of the P-cadherin molecule

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: P-Cadherin

Sujet:

Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin

A431 or PC-3 cells. Human pancreas, placenta or prostate.

Poids moléculaire: 116kDa

ID gène: 1001, 191842

UniProt: P22223