Recombinant Selectin E/CD62e anticorps

N° du produit ABIN7865478

Cet anticorps Souris Monoclonal détecte spécifiquement Selectin E/CD62e dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Selectin E/CD62e anticorps (ABIN7865478)

Antigène: Selectin E/CD62e (SELE) (Selectin E (SELE))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Selectin E/CD62e est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: R16G4

Détail du produit anti-Selectin E/CD62e anticorps

Expression System: CHO Cells

Fonction: Recombinant CD62E / Selectin E (SELE) / ELAM-1 Antibody

Specificité: CD62E is also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) or E-selectin. It is a type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L and CD62P). CD62E is expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial tethering and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. The main ligands recognized by CD62E are oligosaccharides related to sialyl-lewis X.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Prokaryotic recombinant fusion protein corresponding to the cysteine-rich complement control protein domains of the CD62E molecule

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Selectin E/CD62e

Antigène: Selectin E/CD62e (SELE) (Selectin E (SELE))

Autre désignation: CD62E

Sujet:

CD62E, ELAM1, SELE, E-selectin, ELAM-1, LECAM2

Human bone marrow, lymph node, inflamed tonsil, heart or liver.

Poids moléculaire: 115kDa

ID gène: 6401

UniProt: P16581

Pathways: Thromboxane A2 Receptor Signaling