Recombinant CD99 anticorps (AA 1-185)

N° du produit ABIN7864302

Cet anticorps anti-CD99 Monoclonal Souris (Clone rMIC2-8746) (ABIN7864302) détecte spécifiquement CD99 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD99 anticorps (AA 1-185) (ABIN7864302)

Antigène: CD99

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD99 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RMIC2-8746

Détail du produit anti-CD99 anticorps

Épitope: AA 1-185

Fonction: Recombinant CD99 / MIC2 (Ewing s Sarcoma Marker) Antibody

Specificité: Recognizes a sialoglycoprotein of 27-32 kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32 kDa (p30/32). 79oΩAlthough its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis. 79oΩCD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing s sarcoma cells and primitive peripheral neuroectodermal tumors.

Purification: 200ug/ml of Ab purified by Protein A Column.

Immunogène: Recombinant fragment (around aa1-185) of human MIC2 protein (exact sequence is proprietary)

Isotype: IgM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CD99

Antigène: CD99

Autre désignation: CD99

Sujet:

12E7, E2 antigen, MIC 2X, MIC 2Y, MIC2, Protein MIC2, Surface antigen MIC2, T-cell surface glycoprotein E2

Human pancreas or Ewing s Sarcoma.

Poids moléculaire: 27-32kDa

ID gène: 4267, 653349

UniProt: P14209