Recombinant beta Catenin anticorps (AA 1-200)
Aperçu rapide pour Recombinant beta Catenin anticorps (AA 1-200) (ABIN7857921)
Antigène
Voir toutes beta Catenin (CATNB) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-200
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Fonction
- Recombinant Catenin, beta (CTNNB1) Antibody
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Specificité
- Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, beta-catenin is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution of beta-catenin throughout the cytoplasm results in a diffuse cytoplasmic pattern. Immuno-staining of beta-catenin and E-cadherin is helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic beta-catenin staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.
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Purification
- 200ug/ml of Ab purified by Protein A Column.
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Immunogène
- Recombinant fragment (around aa1-200) of human CTNNB1 protein (exact sequence is proprietary)
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Isotype
- IgG, kappa
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anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB Reactivité: Humain, Souris, Rat WB, FACS, ELISA, IF (cc), IHC (p), IF (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 661-781) antibodyCATNB Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Porc WB, FACS, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet, Chien, Porc, Lapin, Mouton, Singe, Hamster, Avian, Cat, Âne, Chévre, Cobaye, Cheval WB, IF, IHC (p), IHC (fro) Hôte: Chèvre Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reactivité: Humain, Poisson zèbre (Danio rerio) WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 725-775) antibodyCATNB Reactivité: Humain, Souris WB, IHC, FACS, IF (p), ICC, IP Hôte: Lapin Monoclonal BLR086G unconjugated Recombinant Antibody
anti-Catenin, beta (CATNB) antibodyCATNB Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio) WB, IHC, IF Hôte: Souris Monoclonal unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reactivité: Humain, Souris, Rat WB, IHC Hôte: Souris Monoclonal 4A3H3 unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reactivité: Humain WB, IHC, ICC, IP Hôte: Souris Monoclonal C11 unconjugated
anti-Catenin, beta (CATNB) (AA 760-781) antibodyCATNB Reactivité: Humain, Souris IHC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Autre désignation
- Catenin, beta
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Sujet
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Cadherin associated protein, beta 1 88 kDa, Catenin beta-1, CATNB, CHBCAT, CTNNB1
Human breast carcinoma or prostate.
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Poids moléculaire
- 92kDa
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ID gène
- 1499, 476018
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Pathways
- Peptide Hormone Metabolism
Antigène
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