Recombinant TCP1 alpha/CCTA anticorps (AA 1-200)

N° du produit ABIN7857933

L’anticorps anti-TCP1 alpha/CCTA Monoclonal Souris est utilisé pour la détection de TCP1 alpha/CCTA dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant TCP1 alpha/CCTA anticorps (AA 1-200) (ABIN7857933)

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCP1 alpha/CCTA est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RP40-8765

Détail du produit anti-TCP1 alpha/CCTA anticorps

Épitope: AA 1-200

Fonction: Recombinant p63 (Squamous, Basal & Myoepithelial Cell Marker) Antibody

Specificité: P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

Purification: 200ug/ml of Ab purified by Protein A Column.

Immunogène: Recombinant fragment (around aa1-200) of human TP63 protein (exact sequence is proprietary)

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur TCP1 alpha/CCTA

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Autre désignation: p63

Sujet:

Amplified in squamous cell carcinoma (AIS), Chronic ulcerative stomatitis protein (CUSP), EEC3, Keratinocyte transcription factor KET, LMS, NBP, p40, P51/P63, p53 like transcription factor, p53-related protein p63, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, TP63, TP73, TP73L, Transformation-related protein 63, Trp53rp1, Trp6,3

Human prostate|lung or bladder squamous cell carcinoma tissue.

Poids moléculaire: 63kDa

ID gène: 8626, 137569

UniProt: Q9H3D4