Tyrosinase-Related Protein 1 anticorps (AA 200-400)

N° du produit ABIN7857990

L’anticorps anti-Tyrosinase-Related Protein 1 Monoclonal Lapin est utilisé pour la détection de Tyrosinase-Related Protein 1 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (AA 200-400) (ABIN7857990)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: TYRP1-8313R

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps

Épitope: AA 200-400

Fonction: Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Antibody

Specificité: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. 79oΩRecent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Purification: 200ug/ml of Ab purified by Protein A.

Immunogène: Recombinant fragment (around aa200-400) of human TYRP1 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: Tyrosinase-Related Protein-1

Sujet:

5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP

SK-MEL-19|SK-MEL-23|SK-MEL-30 or SK-MEL-37 cells. Human melanoma.

Poids moléculaire: 75kDa

ID gène: 7306, 270279

UniProt: P17643