Recombinant EpCAM anticorps (Cytoplasmic Domain)

N° du produit ABIN7863105

Cet anticorps anti-EpCAM Monoclonal Lapin (Clone EGP40-7035R) (ABIN7863105) détecte spécifiquement EpCAM dans IHC. L’anticorps est réactif avec des échantillons de Humain, Cat et Chien.

Aperçu rapide pour Recombinant EpCAM anticorps (Cytoplasmic Domain) (ABIN7863105)

Antigène: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Cat, Chien

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EpCAM est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: EGP40-7035R

Détail du produit anti-EpCAM anticorps

Épitope: AA 289-314, Cytoplasmic Domain

Fonction: Recombinant EpCAM / CD326 (Cytoplasmic Domain) (Epithelial Marker) Antibody

Specificité: Epitope of this MAb is mapped between aa 202-212 of EGP40, which is a 40-43 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. Antibody to Ep-CAM has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Purification: 200ug/ml of Ab purified by Protein A.

Immunogène: Recombinant fragment from cytoplasmic domain (around aa 289-314) of human EpCAM (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur EpCAM

Antigène: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Autre désignation: EpCAM

Sujet:

Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, EGP2, EGP314, ESA, Epithelial Glycoprotein 314, KSA, TROP1, Epithelial Cell Adhesion Molecule, Tumor-associated Calcium Signal Transducer 1 (TACSTD1)

HT29 cells. Human colon or breast., MCF-7

Poids moléculaire: 40-43kDa

ID gène: 4072, 542050

UniProt: P16422