IL-10 anticorps

N° du produit ABIN7864942

L’anticorps anti-IL-10 Monoclonal Souris est utilisé pour la détection de IL-10 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour IL-10 anticorps (ABIN7864942)

Antigène: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-10 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: IL10-8711

Détail du produit anti-IL-10 anticorps

Fonction: Interleukin 10 (IL10) (Immuno-regulation Marker) Antibody

Specificité: Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Purification: 200ug/ml of Ab purified by Protein A.

Immunogène: Recombinant full-length human Interleukin 10 (IL10) protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur IL-10

Antigène: IL-10 (IL10) (Interleukin 10 (IL10))

Autre désignation: Interleukin 10

Sujet:

Cytokine Synthesis Inhibitory Factor (CSIF), GVHDS, IL-10, IL10, IL10A, Interleukin-10, T-cell Growth Inhibitory Factor (TGIF)

Human adrenal or lymph node tissues (IHC).

Poids moléculaire: 20kDa (Monomer), 37kDa (Dimer)

ID gène: 3586, 193717

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints