Recombinant Uroplakin 2 anticorps (AA 36-51)

N° du produit ABIN7858041

L’anticorps anti-Uroplakin 2 Monoclonal Lapin est utilisé pour la détection de Uroplakin 2 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant Uroplakin 2 anticorps (AA 36-51) (ABIN7858041)

Antigène: Uroplakin 2 (UPK2)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Uroplakin 2 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: UPK2-13669R

Détail du produit anti-Uroplakin 2 anticorps

Épitope: AA 36-51

Fonction: Recombinant Uroplakin II (UPK2) (Urothelial Differentiation Marker) Antibody

Specificité: Uroplakin II (UPII) is a 15- kDa protein comprising urothelial plaques, which fortify the urothelial barrier. It is a highly specific marker for tumors of urothelial origin, particularly urothelial carcinoma (UC). UPII messenger RNA has been detected in the tissue and blood of UC patients. Immunohistochemistry utilizing UPII antibodies, such as UPK2/13669R, exhibits high specificity and increased sensitivity for urothelial carcinoma compared to UPIII antibodies. UPII immunohistochemistry is valuable for differentiating urothelial carcinoma from other malignancies, including prostate adenocarcinoma or metastatic breast carcinoma. It has also shown promise for detecting micrometastases of bladder cancer. UPII expression is found in various UC subtypes like micro-papillary, plasmacytoid, and sarcomatoid variants.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A.

Immunogène: Recombinant fragment (around aa 36-51) of human Uroplakin 2 (UPK2) protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Uroplakin 2

Antigène: Uroplakin 2 (UPK2)

Autre désignation: Uroplakin II

Sujet:

UP2, UPII

Urinary bladder.

Poids moléculaire: 195kDa

ID gène: 7379

UniProt: O00526