Recombinant Podoplanin anticorps (AA 1-100)
Aperçu rapide pour Recombinant Podoplanin anticorps (AA 1-100) (ABIN7864272)
Antigène
Voir toutes Podoplanin (PDPN) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-100
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Fonction
- Recombinant Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody
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Specificité
- It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumÇ 79oΩas well as lymphoangiomas,Ç 79oΩKaposi sarcomas,Ç 79oΩand in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant human Podoplanin (PDPN) protein fragment (around aa 1-100) (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Podoplanin (PDPN)
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Autre désignation
- Podoplanin
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Sujet
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Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8,
HeLa cells. Human cervical or lung carcinoma.
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Poids moléculaire
- 38-43kDa
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ID gène
- 10630, 468675
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UniProt
- Q86YL7
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Pathways
- Dicarboxylic Acid Transport
Antigène
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