Fatty Acid Binding Protein anticorps (AA 1-127)
Aperçu rapide pour Fatty Acid Binding Protein anticorps (AA 1-127) (ABIN7858191)
Antigène
Voir toutes Fatty Acid Binding Protein (FABP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-127
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Fonction
- Fatty Acid Binding Protein (Liver) / FABP1 Antibody
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Specificité
- Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Human recombinant FABP1 protein fragment (around aa1-127) (exact sequence is proprietary)
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Fatty Acid Binding Protein (FABP)
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Autre désignation
- Fatty Acid Binding Protein
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Sujet
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FABP1, L-FABP
Liver or colon carcinoma tissues (IHC). Human kidney tissue lysate (WB).
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Poids moléculaire
- 14kDa
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ID gène
- 2168, 380135
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UniProt
- P07148
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Pathways
- Chromatin Binding, Monocarboxylic Acid Catabolic Process
Antigène
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