Cofilin 2 anticorps (AA 1-166)

N° du produit ABIN7865261

Cet anticorps Souris Monoclonal détecte spécifiquement Cofilin 2. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cofilin 2 anticorps (AA 1-166) (ABIN7865261)

Antigène: Cofilin 2 (CFL2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cofilin 2 est non-conjugé

Application: Veuillez nous consulter SVP

Clone: CFL2-9963

Détail du produit anti-Cofilin 2 anticorps

Épitope: AA 1-166

Fonction: CFL2 / NEM7 Antibody

Specificité: Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser-3 by factors such as opsonized zymosan. Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa1-166) of human CFL2 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Cofilin 2

Antigène: Cofilin 2 (CFL2)

Autre désignation: CFL2

Sujet: NEM7

Poids moléculaire: 19-21kDa

ID gène: 1073, 180141

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis