Centrin 1 anticorps (AA 1-172)

N° du produit ABIN7865280

Cet anticorps anti-Centrin 1 Monoclonal Souris (Clone CETN1-9878) (ABIN7865280) détecte spécifiquement Centrin 1 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Centrin 1 anticorps (AA 1-172) (ABIN7865280)

Antigène: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Centrin 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: CETN1-9878

Détail du produit anti-Centrin 1 anticorps

Épitope: AA 1-172

Fonction: CETN1 / Centrin-1 Antibody

Specificité: Centrin-1 Antibody (2A6) is an IgG₁X mouse monoclonal Centrin-1 antibody (also designated Caltractin isoform 2 antibody or CETN1 antibody) that detects the Centrin-1 protein of human origin by WB, IP and ELISA. Centrin-1 Antibody (2A6) is available as the non-conjugated anti-Centrin-1 antibody. EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle, and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles, and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa1-172) of human CETN1 protein (exact sequence is proprietary)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Centrin 1

Antigène: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Autre désignation: CETN1

Sujet: CEN1, CETN

Poids moléculaire: 20KDa

ID gène: 1068, 122511

UniProt: Q12798