IL18R1 anticorps (AA 1-200)
Aperçu rapide pour IL18R1 anticorps (AA 1-200) (ABIN7864578)
Antigène
Voir toutes IL18R1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-200
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Fonction
- IL18R1 Antibody
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Specificité
- Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-é 79oΩ production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1± or IL-1≤. The association of IL-18 to IL-18R leads to activation of NFé 79oΩB. At present two subunits of IL-18R have been characterized: IL-18R± and IL-18R≤. IL-18R± has been described as the ligand-binding chain and IL-18R≤ as the signal-transduction chain.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa1-200) of human IL18R1 protein (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- IL18R1 (Interleukin 18 Receptor 1 (IL18R1))
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Autre désignation
- IL18R1
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Sujet
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CD218 antigen-like family member A, CDw218a antigen, IL-18R1, IL-1Rrp, IL1 receptor-related protein, Il18ralpha,IL1R-rp, IL1RRP, Interleukin 18 receptor, alpha chain
Human lung|leukocytes|liver or thymus.|spleen
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Poids moléculaire
- 62kDa
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ID gène
- 8809, 469521
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UniProt
- Q13478
Antigène
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