Recombinant MYH11 anticorps (AA 1-200)
Aperçu rapide pour Recombinant MYH11 anticorps (AA 1-200) (ABIN7858628)
Antigène
Voir toutes MYH11 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-200
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Fonction
- Recombinant Smooth Muscle Myosin Heavy Chain (SM-MHC)(Leiomyosarcoma & Myoepithelial Cell Marker) Antibody
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Specificité
- Smooth Muscle Myosin, heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early and is specific for smooth muscle development. SM-MHC stains the intact myoepithelial cell (MEC) layers present in benign and in situ malignant breast and bronchioloalveolar lesions and is therefore very helpful in distinguishing between benign and malignant tumors. The antibody reacts with smooth muscle cells and myoepithelial cells, but not with myofibroblasts. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa1-200) of human MYH11 protein (exact sequence is proprietary)
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
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Autre désignation
- Smooth Muscle Myosin Heavy Chain
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Sujet
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AAT4, Myosin heavy chain 11 (MYH11), Myosin heavy chain 11 smooth muscle, Smooth muscle myosin heavy chain 11, Myosin-11, SM1, SM2, SMHC, SMMHC
Human smooth muscle|uterus or breast.
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Poids moléculaire
- 227kDa
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ID gène
- 4629, 460109
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UniProt
- P35749
Antigène
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