PON1 anticorps (AA 1-200)

N° du produit ABIN7864406

Cet anticorps Souris Monoclonal détecte spécifiquement PON1 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PON1 anticorps (AA 1-200) (ABIN7864406)

Antigène: PON1 (Paraoxonase 1 (PON1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PON1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: PON1-1351

Détail du produit anti-PON1 anticorps

Épitope: AA 1-200

Fonction: PON1 / Paraoxonase 1 Antibody

Specificité: Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa1-200) of human PON1 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur PON1

Antigène: PON1 (Paraoxonase 1 (PON1))

Autre désignation: PON1

Sujet:

A-esterase 1, Aromatic esterase 1, Arylesterase 1, Arylesterase B type, ESA, Esterase A, K 45, MVCD5, Paraoxonase 1, Paraoxonase B type, Paraoxonase, plasma, Serum aryldialkylphosphatase 1, Serum paraoxonase/arylesterase 1

Human liver.

Poids moléculaire: 43kDa

ID gène: 5444, 370995

UniProt: P27169