T-Bet anticorps (AA 1-200)

N° du produit ABIN7864466

L’anticorps anti-T-Bet Monoclonal Souris est utilisé pour la détection de T-Bet dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour T-Bet anticorps (AA 1-200) (ABIN7864466)

Antigène: T-Bet

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp T-Bet est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: TBX21-6724

Détail du produit anti-T-Bet anticorps

Épitope: AA 1-200

Fonction: T-bet / Tbox-bet / TBX21 Antibody

Specificité: T helper (Th) lymphocytes differentiate into two unique subsets, Th1 and Th2, which differ both in function and in the cytokines they secrete. Th1 and Th2 cytokines promote the growth and differentiation of their subset, and inhibit the growth and differentiation of the opposing subset. T-bet (T-box expressed in T cells) is a Th1-specific T-box transcription factor that controls the expression of the Th1 cytokine, IFN-g. T-bet also converts effector Th2 cells into the opposing Th1 subset. T-bet is selectively expressed in Th1 cells. The level of T-bet expression is increased by signals mediated by the T cell receptor (TCR). IL-12 also induces an increase in the level of T-bet. T-bet was originally isolated from nuclear extracts of resting and PMA/ionomycin-activated AE7 cells. It is expressed in low levels in AE7 cells, and in increased levels in stimulated AE7.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 1-200) of human TBX21 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur T-Bet

Antigène: T-Bet

Sujet:

T box expressed in T cells, T box protein 21, T box transcription factor TBX21, T cell specific T box transcription factor T bet, T PET, T-cell-specific T-box transcription factor T-bet, TBET, TBLYM, TPET, Transcription factor TBLYM

Human tonsil|non-Hodgkin s lymphoma or spleen. T-cell specific.

Poids moléculaire: 62kDa

ID gène: 30009, 272409

UniProt: Q9UL17