KCNIP2 anticorps (AA 1-270)

N° du produit ABIN7864996

Cet anticorps anti-KCNIP2 Monoclonal Souris (Clone KCNIP2-7588) (ABIN7864996) détecte spécifiquement KCNIP2 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour KCNIP2 anticorps (AA 1-270) (ABIN7864996)

Antigène: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KCNIP2 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: KCNIP2-7588

Détail du produit anti-KCNIP2 anticorps

Épitope: AA 1-270

Fonction: KCNIP2 / KCHIP2 Antibody

Specificité: In the brain and heart, rapidly inactivating (A-type) voltage-gated potassium (Kv) currents control the excitability of neurons and cardiac myocytes. KChIPs are Kv channel-interacting proteins that bind to the cytoplasmic amino termini of Kv4±-subunits and are integral components of native Kv4 channel complexes. KChIP family members include KChIP1 expressed in brain, KChIP2 expressed in heart, brain, and lung, and KChIP3 (previously identified as calsenilin) expressed in brain and testis. In rat brain, KChIP1 colocalizes with Kv4.3 in granule cells and KChIP2 colocalizes with Kv4.2 in both neocoritcal and subcortical structures. The KChIPs are members of the recoverin/neuronal calcium sensor-1 subfamily of calcium-binding proteins and show 99 % nucleotide homology to DREAM, suggesting that KChIPs may have activity beyond modulation of Kv4 channels.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa1-270) of human KCNIP2 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur KCNIP2

Antigène: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Autre désignation: KCNIP2

Sujet:

A type potassium channel modulatory protein 2, Cardiac voltage gated potassium channel modulatory subunit, DKFZp566L1246, KChIP2, Kcnip2, Kv channel interacting protein 2, Potassium channel interacting protein 2

Human brain.

Poids moléculaire: 27-36kDa

ID gène: 30819, 97044

UniProt: Q9NS61